Phoenix, Arizona (UroToday.com) At the meeting titled "The Interval of Fasting, Metabolism, and Cancer Risk," Dr. Marinac on the...
He went on to talk about the women's nutrition and healthy living study, which was a randomized controlled intervention trial involving 3,088 breast cancer survivors. Patients were followed longitudinally and the measurements repeated at the beginning of the study, 1 and 4 years. The clinical outcomes were breast cancer (7.3 years follow-up) and mortality (cancer-specific and general).
- The duration of the night fasting was estimated from food withdrawals with a timestamp.
- The recurrence of breast cancer was significantly lower in patients with nocturnal fasting of> = 13 hours than in <13 hours.
- HR for breast cancer-specific survival (fasting all night> = 13 hours versus <13 hours): HR 1.21, p = 0.19
- There was also no difference in overall mortality
After 1 month, they found the following results:
Although this was not planned (and the patients were not listed as potential benefit), they found a weight loss of 1 kg in one month regardless of the breed. The average nocturnal fast was 13-13.2 hours, based on 10.6-10.8 hours. There was no difference depending on the race.
More important:
- 90% said fasting was easy
- 90% said they could fast for more than 12 hours
- 70% said they preferred SMS over the phone.
- 90% found the fast something pleasant
Takeaway statement: Prolonged nocturnal fasting may be a strategy to reduce cancer risk, as well as excessive morbidity and mortality in cancer survivors.
Submitted by: Catherine Marinac, PhD, Dana-Farber Cancer Institute, Boston
Written by: Dr. med. Thenappan Chandrasekar, clinical instructor, Thomas Jefferson University, Twitter: @tchandra_uromd at the Nineteenth Annual Meeting of the Urological Oncology Society (OUA), 28-30. November 2018, Phoenix, Arizona
