Phoenix, Arizona (UroToday.com) During the session "Interval Between Fasting, Metabolism, and Cancer Risk", Dr. Marinac on the c...
He then spoke about the study on healthy eating and healthy living for women, a randomized controlled intervention study involving 3,088 breast cancer survivors. The patients were followed lengthways and the measurements were repeated at the beginning of the study after 1 and 4 years. The evaluated clinical endpoints were breast cancer events (7.3 years follow-up) and mortality (cancer-specific and general).
- The duration of night fasting was estimated from food withdrawals with a time stamp
- The recurrence of breast cancer was significantly less in patients with an overnight fast of> = 13 hours compared to <13 hours
- HR for breast cancer-specific survival (fasting overnight> = 13 hours versus <13 hours): HR 1.21, p = 0.19
- There was no difference in all-cause mortality either
After 1 month, they found the following results:
Although this was not expected (and the patients were not declared to be of potential benefit), they found a weight loss of 1 kg in 1 month, regardless of race. The average speed at night was 13 to 13.2 hours compared to a baseline of 10.6 to 10.8 hours. There was no difference depending on the race.
More important:
- 90% said fasting was easy
- 90% said they could fast> 12 hours
- 70% indicated that they preferred text messages to telephone advice.
- Fasting was very pleasant for 90%
Take-home statement: Prolonged fasting at night can be a strategy to reduce the risk of cancer and the excessive morbidity and mortality of cancer survivors.
Submitted by: Catherine Marinac, PhD, Dana Farber Cancer Institute, Boston
Written by: Dr. med. Thenappan Chandrasekar, clinical instructor, Thomas Jefferson University, twitter: @tchandra_uromd at the 19th Annual Meeting of the Urological Oncology Society (SUO) November 28-30, 2018 in Phoenix, Arizona
